Research
Research Area
- Development of organic synthesis methodology using nitrogen-oxygen containing compounds: nitro compounds, nitronates, nitrosoacetals.
- Total synthesis of biologically active compounds based on the developed transformations.
- Synthesis and study of properties of novel heterocage compounds.
Main research directions
Development of novel methods of functionalization of nitronic acids ethers (nitronates) and their application in total synthesis
New approaches to the functionalization of α- and β-position in nitronates using electrophilic activation of C=NO2 fragment and [3+3]-cycloannelation with 1,3-dipoles were proposed. It was shown that the developed methods can be effectively used in total synthesis.
Reviews
Synthesis 2017, 49, 3255-3268. DOI: 10.1055/s-0036-1589063.
Chem. Rec. 2018, 18, 1489-1500. DOI: 10.1002/tcr.201800009.
Chem. Rev. 2014, 114, 5426-5476. DOI: 10.1021/cr400196x.
Chem. Rev. 2011, 111, 5004-5041. DOI: 10.1021/cr100292w.
Beilstein J. Org. Chem. 2017, 13, 2214-2234. DOI: 10.3762/bjoc.13.220.
Tetrahedron 2016, 72, 6191-6281. DOI: 10.1016/j.tet.2016.07.067.
Isr. J. Chem. 2016, 56, 385-398. DOI: 10.1002/ijch.201500082.
Selected publications
J. Org. Chem. 2018, 83, 11057-11066. DOI: 10.1021/acs.joc.8b01652.
Chem. Eur. J. 2017, 23, 4570-4578. DOI: 10.1002/chem.201605390 (front cover).
Eur. J. Org. Chem. 2016, 5569-5578. DOI: 10.1002/ejoc.201600952.
Org. Lett. 2013, 15, 350-353. DOI: 10.1021/ol303292c.
Eur. J. Org. Chem. 2012, 3377-3384. DOI: 10.1002/ejoc.201200239.
Synthesis 2017, 49, 3255-3268. DOI: 10.1055/s-0036-1589063.
Chem. Rec. 2018, 18, 1489-1500. DOI: 10.1002/tcr.201800009.
Chem. Rev. 2014, 114, 5426-5476. DOI: 10.1021/cr400196x.
Chem. Rev. 2011, 111, 5004-5041. DOI: 10.1021/cr100292w.
Beilstein J. Org. Chem. 2017, 13, 2214-2234. DOI: 10.3762/bjoc.13.220.
Tetrahedron 2016, 72, 6191-6281. DOI: 10.1016/j.tet.2016.07.067.
Isr. J. Chem. 2016, 56, 385-398. DOI: 10.1002/ijch.201500082.
Selected publications
J. Org. Chem. 2018, 83, 11057-11066. DOI: 10.1021/acs.joc.8b01652.
Chem. Eur. J. 2017, 23, 4570-4578. DOI: 10.1002/chem.201605390 (front cover).
Eur. J. Org. Chem. 2016, 5569-5578. DOI: 10.1002/ejoc.201600952.
Org. Lett. 2013, 15, 350-353. DOI: 10.1021/ol303292c.
Eur. J. Org. Chem. 2012, 3377-3384. DOI: 10.1002/ejoc.201200239.
Development of approaches to generation of fluorinated nitro-derivatives and their use in the synthesis of fluorine-containing heterocycles
The method of synthesis of α-fluoronitroalkenes was proposed. Based on it, methods for the synthesis of various fluorine-containing heterocyclic compounds were developed.
Reviews
Uspekhi khimii 2019, 88, 425-569. DOI: 10.1070/RCR4871.
Selected publications
Org. Biomol. Chem. 2019, 17, 1442-1454. DOI: 10.1039/C8OB03126F.
Org. Chem. Front. 2018, 5, 2588-2594. DOI: 10.1039/C8QO00623G.
J. Org. Chem. 2017, 82, 5274-5284. DOI: 10.1021/acs.joc.7b00578.
Uspekhi khimii 2019, 88, 425-569. DOI: 10.1070/RCR4871.
Selected publications
Org. Biomol. Chem. 2019, 17, 1442-1454. DOI: 10.1039/C8OB03126F.
Org. Chem. Front. 2018, 5, 2588-2594. DOI: 10.1039/C8QO00623G.
J. Org. Chem. 2017, 82, 5274-5284. DOI: 10.1021/acs.joc.7b00578.
Synthesis of novel heterocage compounds
The approach to the construction of new heteroadamantanes on the basis of oxime cyclotrimerization reaction was proposed. Structural isomer of urotropin was obtained for the first time.
Review
Targets in Heterocyclic Systems, Volume 21, Italian Society of Chemistry, Italy, Roma, 2017, pp. 82-97. DOI: 10.17374/targets.2018.21.82.
Selected publications
J. Org. Chem., 2018, 83, 9756-9773 DOI: 10.1021/acs.joc.8b01296.
J. Org. Chem., 2015, 80, 6728-6736. DOI: 10.1021/acs.joc.5b00892.
J. Org. Chem., 2014, 79, 6079-6086. DOI: 10.1021/jo5007703.
Targets in Heterocyclic Systems, Volume 21, Italian Society of Chemistry, Italy, Roma, 2017, pp. 82-97. DOI: 10.17374/targets.2018.21.82.
Selected publications
J. Org. Chem., 2018, 83, 9756-9773 DOI: 10.1021/acs.joc.8b01296.
J. Org. Chem., 2015, 80, 6728-6736. DOI: 10.1021/acs.joc.5b00892.
J. Org. Chem., 2014, 79, 6079-6086. DOI: 10.1021/jo5007703.
